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Table of Contents
LETTER TO THE EDITOR
Year : 2011  |  Volume : 27  |  Issue : 4  |  Page : 573

Comparison of propofol-based anesthesia to conventional inhalational general anesthesia for spine surgery-Few queries


Department of Anaesthesiology, Lokmanya Tilak Municipal Medical College and Lokmanya Tilak Municipal General Hospital, Sion, Mumbai - 400 077, India

Date of Web Publication24-Oct-2011

Correspondence Address:
Anila D Malde
Block No. 3, Nagjibhai Mansion, Manubhai P. Vaidya Marg, Ghatkopar (East), Mumbai
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9185.86619

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How to cite this article:
Malde AD. Comparison of propofol-based anesthesia to conventional inhalational general anesthesia for spine surgery-Few queries. J Anaesthesiol Clin Pharmacol 2011;27:573

How to cite this URL:
Malde AD. Comparison of propofol-based anesthesia to conventional inhalational general anesthesia for spine surgery-Few queries. J Anaesthesiol Clin Pharmacol [serial online] 2011 [cited 2019 Oct 15];27:573. Available from: http://www.joacp.org/text.asp?2011/27/4/573/86619

Sir,

I read with interest the article "Comparison of Propofol Based Anaesthesia to Conventional Inhalational General Anaesthesia for Spine Surgery" by Mishra et al. [1] I have carried out similar work in the pediatric age group and have the following queries and comments.

Mishra et al. aimed to compare hemodynamic stability in both the groups; however, in the results, there is no table or graph depicting the same. They have stated that the heart rate (HR) remained >20% below baseline value in the propofol group; HR was almost same as before induction in inhalational group; and that incidence of hypotension was almost same in both the groups. No data have been presented for incidence of bradycardia requiring treatment in propofol group, or for hypertension in inhalational group. The authors have not shown any data justifying their statement that hemodynamic profile of the study group was better than control group.

The authors also aimed to compare early emergence. However, there is no mention of the time to orientation and there are no objective criteria for defining clear headed recovery. Time to extubation was lesser than time to limb lift. Results do not mention the incidence of postoperative nausea vomiting in both the groups, though it is mentioned in the abstract and discussion. Methodology does mention that total dose of propofol and isoflurane consumed during the procedure was noted. However, the mean ± SD dose of either drug or the total dose of isoflurane used per case is not shown in the results. An average 400 mg of propofol was required, but there is no mention of the cost of propofol remaining, (which must have been discarded) at the end of the case. The demographic data including duration of surgery or type of spine surgery are not mentioned at all. Assuming average weight of adult as 60 kg, duration of surgery of 2.5 hours, induction dose as 150 mg, maintenance dose of 250 mg (1.66 mg/kg/hr) propofol must have been used. I feel the dose was less considering that patients were not given any benzodiazepine at all, but surprisingly, the bispectral index remained between 40 and 60.

 
   References Top

1.Mishra LD, Pradhan SK, Pradhan CS. Comparison of propofol based anaesthesia to conventional inhalational general anaesthesia for spine surgery. J Anaesth Clin Pharmacol 2011;27:59-61.  Back to cited text no. 1
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1 RE: Comparison of propofolbased anesthesia to conventional inhalational general anesthesia for spine surgery-Few queries
Mishra, L.D., Pradhan, S.K., Pradhan, C.S.
Journal of Anaesthesiology Clinical Pharmacology. 2011; 27(4): 573-574
[Pubmed]



 

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