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REVIEW ARTICLE
Year : 2014  |  Volume : 30  |  Issue : 1  |  Page : 7-9

Considerations in perioperative assessment of valproic acid coagulopathy


Department of Anesthesiology, Children's National Medical Center, The George Washington University Medical Center, NW Washington, DC, USA

Correspondence Address:
Claude Abdallah
Department of Anesthesiology, Children's National Medical Center, The George Washington University Medical Center, 111 Michigan Avenue, NW Washington, DC 20010-2970
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0970-9185.125685

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Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect.


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