Year : 2019 | Volume
: 35 | Issue : 2 | Page : 236--241
Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial
Tilak Perika1, Suman Lata Gupta1, Lenin Babu Elakkumanan1, Shivanand Kattimani2
1 Department of Anaesthesiology and Cirtical Care, JIPMER, Puducherry, India
2 Department of Psychiatry, JIPMER, Puducherry, India
Background and Aims: Early psychomotor recovery is an essential part of day care surgery which depends on brain integration of motor and sensory co-ordination. Even though dexmedetomidine is commonly used for day care procedures, the recovery profile was not studied. Hence, this study was designed to evaluate the psychomotor recovery of sedation with dexmedetomidine during spinal anesthesia.
Material and Methods: Sixty-six patients were included. Group D received dexmedetomidine 0.5 μg/kg (loading dose) followed by 0.2–1 μg/kg/hour. Group P received propofol infusion of 25–100 μg/kg/minute. Psychomotor recovery was assessed by finger-tapping, manual dexterity, visual spatial memory capacity, and pen and paper tests. Psychomotor tasks were given to the patients postoperatively at every 30 minutes for 2 hours followed by every hour up to 4 hours after surgery. Distribution of patients, age, weight, duration of surgery, and the level of sensory blockade was compared using independent t-test. Student's t-test has been used to find the significance of parameters such as heart rate, mean arterial pressure, oxygen saturation (SpO2), psychomotor recovery between two groups. P < 0.05 was considered as significant.
Results: The motor recovery using finger tapping test was faster in Group D than Group P (73.94 ± 42.13 vs 101.21 ± 37.98 minutes, P–value = 0.007). Motor recovery using peg board test was faster in Group P than Group D (82.12 ± 40.37 vs 99.39 ± 43.08 minutes, P–value = 0.098). Visual spatial capacity memory test and pen and paper test were unaffected.
Conclusions: We conclude that patients who received dexmedetomidine showed earlier recovery with finger tapping test. Hence, we suggest to use dexmedetomidine for complete psychomotor recovery and fast-track discharging of the patient after spinal anesthesia.
Suman Lata Gupta
Department of Anaesthesiology and Cirtical Care, JIPMER, Puducherry - 605 005
|How to cite this article:|
Perika T, Gupta SL, Elakkumanan LB, Kattimani S. Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial.J Anaesthesiol Clin Pharmacol 2019;35:236-241
|How to cite this URL:|
Perika T, Gupta SL, Elakkumanan LB, Kattimani S. Psychomotor recovery of dexmedetomidine compared with propofol after sedation during spinal anesthesia: A randomized control trial. J Anaesthesiol Clin Pharmacol [serial online] 2019 [cited 2019 Aug 22 ];35:236-241
Available from: http://www.joacp.org/article.asp?issn=0970-9185;year=2019;volume=35;issue=2;spage=236;epage=241;aulast=Perika;type=0