Users Online: 1568 Home Print this page Email this page Small font sizeDefault font sizeIncrease font size  
Home | About us | Editorial board | Search | Ahead of print | Current issue | Archives | Submit article | Instructions | Subscribe | Contacts | Login 

RSACP wishes to inform that it shall be discontinuing the dispatch of print copy of JOACP to it's Life members. The print copy of JOACP will be posted only to those life members who send us a written confirmation for continuation of print copy.
Kindly email your affirmation for print copies to [email protected] preferably by 30th June 2019.


Table of Contents
Year : 2014  |  Volume : 30  |  Issue : 1  |  Page : 71-77

Significantly reduced hypoxemic events in morbidly obese patients undergoing gastrointestinal endoscopy: Predictors and practice effect

1 Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
2 Department of Anesthesia, Post Graduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Surgery, University of Pennsylvania Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
4 Department of Anesthesiology and Critical Care; Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
5 Department of Anesthesiology and Perioperative Medicine, Drexel University College of Medicine, Hahnemann University Hospital, Philadelphia, PA 19102, USA

Date of Web Publication24-Jan-2014

Correspondence Address:
Basavana Gouda Goudra
Department of Anesthesiology and Critical Care Medicine, 3400 Spruce Street, 680 Dulles Building, Hospital of the University of Pennsylvania, Philadelphia, PA 19104
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0970-9185.125707

Rights and Permissions

Background: Providing anesthesia for gastrointestinal (GI) endoscopy procedures in morbidly obese patients is a challenge for a variety of reasons. The negative impact of obesity on the respiratory system combined with a need to share the upper airway and necessity to preserve the spontaneous ventilation, together add to difficulties.
Materials and Methods: This retrospective cohort study included patients with a body mass index (BMI) >40 kg/m 2 that underwent out-patient GI endoscopy between September 2010 and February 2011. Patient data was analyzed for procedure, airway management technique as well as hypoxemic and cardiovascular events.
Results: A total of 119 patients met the inclusion criteria. Our innovative airway management technique resulted in a lower rate of intraoperative hypoxemic events compared with any published data available. Frequency of desaturation episodes showed statistically significant relation to previous history of obstructive sleep apnea (OSA). These desaturation episodes were found to be statistically independent of increasing BMI of patients.
Conclusion: Pre-operative history of OSA irrespective of associated BMI values can be potentially used as a predictor of intra-procedural desaturation. With suitable modification of anesthesia technique, it is possible to reduce the incidence of adverse respiratory events in morbidly obese patients undergoing GI endoscopy procedures, thereby avoiding the need for endotracheal intubation.

Keywords: Airway, colonoscopy, endoscopic retrograde cholangiopancreatography, endoscopy, morbid obesity

How to cite this article:
Goudra BG, Singh PM, Penugonda LC, Speck RM, Sinha AC. Significantly reduced hypoxemic events in morbidly obese patients undergoing gastrointestinal endoscopy: Predictors and practice effect. J Anaesthesiol Clin Pharmacol 2014;30:71-7

How to cite this URL:
Goudra BG, Singh PM, Penugonda LC, Speck RM, Sinha AC. Significantly reduced hypoxemic events in morbidly obese patients undergoing gastrointestinal endoscopy: Predictors and practice effect. J Anaesthesiol Clin Pharmacol [serial online] 2014 [cited 2021 Apr 18];30:71-7. Available from:

  Introduction Top

"Out of operating room" anesthesia is one of the fastest growing areas of clinical practice. At the Hospital of the University of Pennsylvania, we have had an almost 300% increase [Figure 1] over the last 3 years, much of this attributable to gastrointestinal (GI) endoscopy [Figure 2]. Upper GI endoscopy, in particular, is challenging for the anesthesia provider. The shared airway, increased risk of aspiration, preference for spontaneous ventilation and relative non-availability of rapid help during an emergency due to the remote location, all increase anesthesia risks. The mortality and morbidity is relatively high and is mainly related to airway management. [1] It is to be expected that, morbidly obese patients as a group (individuals with a body mass index [BMI] greater than 40 kg/m 2 ), are likely to have an even higher rate of perioperative complications. Although the American Society of Anesthesia (ASA) recommends that emergency help should be available at all times, [2] it does not specify the quality and nature of emergency support. Again, in the opinion of ASA' task force on perioperative management of patients with obstructive sleep apnea (OSA), general anesthesia with a secured airway is preferable to moderate or deep sedation for most patients with OSA. A significant number of morbidly obese patients presenting for GI endoscopy have OSA. In spite of this, our approach is one of providing intravenous general anesthesia without endotracheal intubation.
Figure 1: Total out of operating room anesthesia case load. EP: Electrophysiological procedures, GI: Gastrointestinal endoscopy, and RAD: Radiological procedures

Click here to view
Figure 2: Gastrointestinal endoscopy case load

Click here to view

The goal of this study was to evaluate the optimum airway management for morbidly obese patients undergoing GI endoscopy under total intravenous anesthesia. In order to understand patient safety and risk in this setting, we evaluated the incidence of complications.

  Materials and Methods Top

This was a retrospective cohort study of morbidly obese (BMI >40 kg/m 2 ) adults who presented for outpatient GI endoscopy over a period of 6 months from September 2010 to February 2011. Patients who were electively intubated for the procedure or under the age of 18 years were not included in this retrospective study. The perioperative records were reviewed to obtain the following patient-specific and procedure specific data: Demographics and comorbidities, method of airway management, endoscopic procedure performed, periods of oxygen saturation below 90 and 95% respectively, cardiovascular complications, unexpected endoscope withdrawal to facilitate patients' oxygenation and any procedure cancellation after the start of the procedure due to anesthesia issues. For statistical analysis, desaturation episode was defined as a fall of pulse oximeter saturation below 95%. Pearson's Chi-square test was used to relate frequency of desaturation to possible predictors (BMI groups and history of OSA). The degree of statistical significance was set at 95% thus taking a P value of less than 0.05 as significant. This retrospective study was approved by the Institutional Review Board of the University of Pennsylvania.

  Results Top

The records of 2035 consecutive patients that underwent outpatient GI endoscopy were reviewed. One hundred nineteen had a BMI greater than 40 and met all inclusion criteria. Characteristics of the 119 individuals included in the cohort are shown in [Table 1]. The majority of patients were female (61.3%). The mean BMI was 45.4 and ranged from 40 to 79.5. All patients in the cohort had co-morbidities, the most common of which was hypertension (68.1%). Pearson's Chi-square test showed a significant correlation between frequency of desaturation (bellow 95% or a 5% fall) and previous history of OSA. (Chi-square = 11.05, P = 0.004, df = 2) with a likelihood ratio of patients with OSA desaturating 5.11 times the patients without OSA. No statistically significant relation could be established between increasing BMI groups [Table 2] and frequency of desaturation (Chi-square = 3.35, P = 0.76).
Table 1: Patient characteristics (N=119)

Click here to view
Table 2: Relation between BMI, history of OSA and procedural complications

Click here to view

The various airway management techniques used are shown in [Table 3]. Nasal trumpet was the most commonly used approach among patients across all BMI [Figure 3]. Complications that occurred within the cohort are shown in [Table 2]. In total, nine individuals experienced periods of oxygen saturation below 95% and two experienced periods of oxygen saturation below 90%. The lowest saturation recorded in one of these two was 89% and another was 82%. The duration of desaturation was very brief. Endoscopy was completed successfully in all patients. One of the patients experienced a very brief ventricular tachycardia that spontaneously reverted to sinus rhythm immediately (no drug administered). There were no airway problems in this patient and oxygenation was 98-99% throughout.
Table 3: Airway types used by BMI group

Click here to view
Figure 3: A size 32 nasal trumpet connected to mapleson‑C breathing system

Click here to view

The duration of the procedure is important in trying to understand the significance of our findings. The mean standard deviation of each of the procedures is in [Table 4]. In general combined esophagogastroduodenoscopy with colonoscopy took much longer. The endoscopic retrograde cholangiopancreatography (ERCP) took longest and our data included all morbidly patients who underwent ERCP during this tile period. Considering the majority of ERCPs were in patients with either pancreatic malignancy or patients who had prior hepatic transplant, the number with morbid obesity was small in this sub group.
Table 4: Relation between duration of the procedure, desaturation and the airway used

Click here to view

The anesthesia technique was a provider and procedure dependent. The majority of patients undergoing upper endoscopy (with or without colonoscopy) were planned with supplemental oxygen through a nasal trumpet (unless anticoagulated or had gross deviated nasal septum). These patients were asked to breathe 100% oxygen with a face mask. In the vast majority (about two thirds), fentanyl (25-50 mcg) was administered 2-3 min before administering propofol. The dose of propofol (between 0.5 and 2 mg/kg) was based on patient's weight, clinical response and comorbidity. As soon as the patients were unresponsive an attempt was made to insert an appropriate sized nasal airway. In the majority of patients, this was successful on first attempt. In a small minority, further administration of oxygen and propofol was required to facilitate tolerance to the insertion of nasal airway. Soon after insertion of the nasal airway, it was connected to the elbow of Mapleson breathing system (an oxygen flow of 8-10 l/min) as seen in [Figure 3]. Anesthesia was maintained on propofol infusion at 80-120 mcg/kg/min. In about one-third of the patients undergoing upper endoscopy, after 2-3 min of preoxygenation, propofol was administered until patient was unresponsive and nasal trumpet was inserted. However, the maintenance phase of anesthesia was achieved with a mixture of propofol and remifentanil (5 mcg of remifentanil mixed with each cc of propofol) started at 100-120 mcg/kg/min of propofol (ignoring any calculation for remifentanil). An effort was always made to time the endoscope insertion at peak clinical effect of propofol, which was usually soon after nasal trumpet was inserted. In some instances, oxygen was administered with nasal cannula at 4-6 l/min and nasal trumpet was inserted if saturations were seen to be dropping. An effort was made to keep the saturation close to 100% at all times. One of the patients was administered oxygen with a handheld jet ventilator via nasal trumpet. Although in this patient group (data collected over about 5 months), supraglottic jet ventilation was used on only one occasion, it is a technique used more often with some anesthesia providers for selected cases and procedures including morbidly obese. A colonoscopy was performed with a laryngeal mask airway and an endoscopy was provided supplemental oxygen with an oral trumpet. The "oral trumpet" refers to the nasal trumpet inserted in the mouth, beside the bite-block between the teeth, due to difficulty in inserting a nasal trumpet. The recovery time, from removal of the endoscope to verbal response, was short (3-5 min) with no unexpected prolongation in any of the patients.

The relation between the BMI and the airway is presented in [Table 3]. As can be appreciated, majority of patients with higher BMI were managed with a nasal trumpet. In additional, [Table 5] shows that patients undergoing upper endoscopy got nasal airways significantly more often than patients undergoing colonoscopy alone. [Table 6] shows the relationship between airway used and BMI for patients undergoing upper GI endoscopy alone. Clearly higher BMI patients were inserted with a nasal trumpet more often than patients with lower BMI.
Table 5: Airway device used for the procedure

Click here to view
Table 6: Relation between BMI and airway used for esophagogastroduodenoscopy with or without colonoscopy

Click here to view

For colposcopies (without esophagogastroduodenoscopy), oxygen was administered with a nasal cannula and the depth of anesthesia was adjusted to preserve the spontaneous ventilation. In case of apnea and (or) desaturation, either face mask or nasal trumpet was inserted.

  Discussion Top

The prevalence of morbid obesity is increasing world-wide. Of all patients presenting for outpatient GI endoscopy in our hospital, nearly 6% were morbidly obese, i.e., had a BMI of over 40 kg/m 2 . We could not find any studies that have specifically reviewed the intraoperative airway management and outcomes in morbidly obese patients presenting for GI endoscopy under anesthesia. However, at least two studies have shown that obese patients run a higher perioperative risk for adverse airway events. In a prospective observational study involving 79 patients undergoing endoscopy under "conscious sedation," Qadeer

et al. [3] found a 51% overall incidence of hypoxemia (defined as saturation below 90% any time during the procedure, irrespective of the duration of hypoxia). They also found a significant difference in the rates of desaturation between non-obese (46%) and obese group (BMI >30 kg/m 2 where it was 71%). In patients undergoing upper GI endoscopy with a BMI of over 28, [4] the baseline oxygen saturations were 94.86 ± 0.63% with a fall to 92.57 ± 1.06% after premedication. Endoscope insertion was associated with a further fall to 90.57 ± 1.27%. The saturation decreased below 90% for about 15% of total endoscopy time. In this study, only patients desaturating below 85% were provided supplemental oxygen. Patients in both of these studies were provided conscious sedation, administered by nurses under the supervision of gastroenterologists. One of the key finding in our study was that BMI did not directly relate to the tendency of desaturation. A logical explanation that distinguishes our finding from the previous studies [4],[5] is that, anesthesiologist rather than gastroenterologists administered sedation in the present cohort. Our finding supports the ASA directive of propofol use only by practitioners trained in airway management (anesthesia providers in our case). Even the highest BMI subgroups (>60 kg/m 2 ) did not show desaturation episodes in our study. Obesity has previously been reported as an independent risk factor for sedation related complications during propofol-mediated anesthesia for advanced endoscopic procedures. [5] In their prospective study, Wani et al. analyzed data of 1016 patients undergoing advanced endoscopic procedures. In obese subgroup, they found an incidence hypoxemia significantly higher than our practice. However, unlike our practice, wherein use of airway maneuvers is considered routine and part of anesthesia practice, Wani et al. used airway manipulations on an as needed basis.

The incidence of diagnosed OSA in our morbidly obese patient population was 64%. Predictably, this incidence increased with increasing severity of obesity, with incidence of 78% in patients above a BMI of 50 kg/m 2 . Although the number of patients with a BMI of over 60 was only 4, the incidence of OSA in this group was 100%. This incidence is similar to the one reported by Frey and Pilcher [6] In morbidly obese patients presenting for bariatric surgery, they found a 71% incidence of OSA. OSA rather than BMI values in our study was found to have significant relation to patients desaturation. OSA leads to significant alterations airway (narrowing) and central nervous system. Small doses of sedatives (propofol) can cause exaggerated response leading to airway obstruction. Thus, both dose titration and airway management are challenging in this subgroup. We were able to bypass the airway obstruction by use of nasal trumpet in these patients, but their physiologically altered responses can still lead to desaturation. Majority of our patients were using CPAP or BIPAP at home. Expectedly, treated OSA patients have a lower incidence of perioperative anesthetic complications, which is highlighted by the fact that patients with the highest OSA associated with highest BMI were not the ones who desaturated, as treatment of OSA probably improves physiological responses to sedation and decreases the likelihood of developing apnea.

The notion that the "administration of supplemental oxygen can suppress respiratory drive", although true, should not, in and of itself, be a reason to avoid administration of supplemental oxygen. Consequently, we suggest that all measures should be taken to prevent hypoxemia especially in morbidly obese with OSA as their functional residual capacity (FRC) is relatively lower and oxygen consumption is relatively higher, on account of higher body weight. In the event of a hypoxemic event, these patients are most challenging to treat as well.

The following is the most likely explanation for incidence of hypoxemia that was significantly less than published study.

  • Practice of using a nasal airway connected to a Mapleson breathing system [Figure 3] allows administration of high concentration of oxygen at the tracheal inlet. High inflow of oxygen at the supraglottic area (10-15 l) could create sufficient positive pressure, thereby preventing the collapse of soft tissue in the velopharynx. This technique also provides apneic insufflation of oxygen thereby delaying hypoxemia and allowing more time to treat apnea/hypopnea
  • Use of supraglottic jet ventilation using a hand held jet device to treat apnea or hypopnea (although in this series, only one patient was supplemented with supraglottic jet ventilation). The actual device and the connections are represented in the picture [Figure 4]. The entrained air from the reservoir bag of the attached breathing system (connected to the nasal trumpet) contains a high percentage of oxygen
  • Ultra morbidly obese are anesthetized and endoscopy performed in supine-head up position. This position can help in preserving FRC by limiting basal lung atelectasis
  • By using a combined opioid (fentanyl-remifentanil)- propofol technique, propofol requirements are reduced and coughing is suppressed. In the majority of the cases, spontaneous ventilation can be maintained.
Figure 4: CO2 out port of an elbow adapter used to deliver supraglottic jet ventilation via nasal trumpet during an endoscopic retrograde cholangiopancreatography

Click here to view

The dose of propofol is controversial in morbidly obese patients. [7],[8] All dosing methods have one aim, to predict the relationship between infusion rates and plasma concentrations (or more accurately, brain concentrations). The various theoretical pharmacokinetic compartments will not increase at the same rate as bodyweight and are likely a function of the percentage of muscle and fat mass, among other factors. The induction dose is likely to be a function of cardiac output with a tendency to use lean body weight for this part of the calculation. However, clearance and volumes of distribution are more likely related to total body weight than lean body weight and the infusions should be based on this. In our study, dosing was largely based on patient's clinical response with the aim of preserving spontaneous respiration. Preserving spontaneous ventilation is important since apnea signifies deeper anesthesia and positive pressure ventilation requires withdrawal of the endoscope in patients undergoing upper GI endoscopies.

Use of remifentanil-propofol mixtures is another controversial area. The mixture is likely to remain stable for at least 30 min. [9] Although the context sensitive halftimes are different for both, given that most GI procedures are under 60 min, it is unlikely to be of any clinical significance. The need to vary the dose of individual components (hypnotic and opioid) is not relevant as GI procedures are not painful like surgeries that involve a skin incision. Based on our findings, propofol along with a short acting opioid, based anesthesia seems to work best in the setting of morbidly obese patients presenting for endoscopy.

Several studies have looked at the mode of delivery of supplementary oxygen for patients undergoing upper GI endoscopy. [10],[11],[12],[13],[14],[15] No data is available regarding the best mode of delivery of supplementary oxygen for patients undergoing GI endoscopy let alone morbidly obese patients. Based on our findings, we recommend a sequence of "preoxygenation-induction-insertion of nasal trumpet (connected to a Mapleson-C breathing system)-gastroduodenoscope insertion" for all upper GI endoscope procedures in morbidly obese patients.

Our study could be criticized for its retrospective nature. However, to do a study of this nature prospectively will be extremely difficult. Moreover, the results may be confounded by the presence of an observer. It might be ethically challenging to do a prospective study in this high risk area of anesthesia.

  Conclusions Top

Increasing BMI does not bear direct correlation to the likelihood of patient's desaturating under sedation for GI procedures. Preoperative history of OSA irrespective of associated BMI values can be potentially used as a predictor of intra-procedural desaturation. With suitable modification of anesthesia technique, it is possible to reduce the incidence of adverse respiratory events in morbidly obese patients undergoing GI endoscopy procedures. Contrary to popular teaching, it is possible to anesthetize these patients without endotracheal intubation. The need to abort the procedure or withdraw the endoscope to facilitate treatment of apnea or hypopnea can be minimized.

  Acknowledgement Top

Mr. Divakara Gouda, Cherry East High School, NJ, USA.

  References Top

1.Metzner J, Posner KL, Domino KB. The risk and safety of anesthesia at remote locations: The US closed claims analysis. Curr Opin Anaesthesiol 2009;22:502-8.  Back to cited text no. 1
2.Gross JB, Bachenberg KL, Benumof JL, Caplan RA, Connis RT, Coté CJ, et al. Practice guidelines for the perioperative management of patients with obstructive sleep apnea: A report by the American Society of Anesthesiologists Task Force on Perioperative Management of patients with obstructive sleep apnea. Anesthesiology 2006;104:1081-93.  Back to cited text no. 2
3.Qadeer MA, Rocio Lopez A, Dumot JA, Vargo JJ. Risk factors for hypoxemia during ambulatory gastrointestinal endoscopy in ASA I-II patients. Dig Dis Sci 2009;54:1035-40.  Back to cited text no. 3
4.Dhariwal A, Plevris JN, Lo NT, Finlayson ND, Heading RC, Hayes PC. Age, anemia, and obesity-associated oxygen desaturation during upper gastrointestinal endoscopy. Gastrointest Endosc 1992;38:684-8.  Back to cited text no. 4
5.Wani S, Azar R, Hovis CE, Hovis RM, Cote GA, Hall M, et al. Obesity as a risk factor for sedation-related complications during propofol-mediated sedation for advanced endoscopic procedures. Gastrointest Endosc 2011;74:1238-47.  Back to cited text no. 5
6.Frey WC, Pilcher J. Obstructive sleep-related breathing disorders in patients evaluated for bariatric surgery. Obes Surg 2003;13:676-83.  Back to cited text no. 6
7.Lemmens HJ. Perioperative pharmacology in morbid obesity. Curr Opin Anaesthesiol 2010;23:485-91.  Back to cited text no. 7
8.Ingrande J, Brodsky JB, Lemmens HJ. Lean body weight scalar for the anesthetic induction dose of propofol in morbidly obese subjects. Anesth Analg 2011;113:57-62.  Back to cited text no. 8
9.Stewart JT, Warren FW, Maddox FC, Viswanathan K, Fox JL. The stability of remifentanil hydrochloride and propofol mixtures in polypropylene syringes and polyvinylchloride bags at 22 degrees-24 degrees C. Anesth Analg 2000;90:1450-1.  Back to cited text no. 9
10.Bell GD, Bown S, Morden A, Coady T, Logan RF. Prevention of hypoxaemia during upper-gastrointestinal endoscopy by means of oxygen via nasal cannulae. Lancet 1987;1:1022-4.  Back to cited text no. 10
11.Brandl S, Borody TJ, Andrews P, Morgan A, Hyland L, Devine M. Oxygenating mouthguard alleviates hypoxia during gastroscopy. Gastrointest Endosc 1992;38:415-7.  Back to cited text no. 11
12.Basavana G. Goudra, Preet Mohinder Singh, and Ashish C. Sinha, "Anesthesia for ERCP: Impact of Anesthesiologist's Experience on Outcome and Cost," Anesthesiology Research and Practice, vol. 2013, Article ID 570518, 5 pages, 2013. doi: 10.1155/2013/570518  Back to cited text no. 12
13.Goudra BG, Singh PM, Sinha AC. Outpatient endoscopic retrograde cholangiopancreatography: Safety and efficacy of anesthetic management with a natural airway in 653 consecutive procedures. Saudi J Anaesth 2013;7:259-65.  Back to cited text no. 13
  Medknow Journal  
14.Bell GD, Quine A, Antrobus JH, Morden A, Burridge SM, Coady TJ, et al. Upper gastrointestinal endoscopy: A prospective randomized study comparing continuous supplemental oxygen via the nasal or oral route. Gastrointest Endosc 1992;38:319-25.  Back to cited text no. 14
15.Wang CY, Ling LC, Cardosa MS, Wong AK, Wong NW. Hypoxia during upper gastrointestinal endoscopy with and without sedation and the effect of pre-oxygenation on oxygen saturation. Anaesthesia 2000;55:654-8.  Back to cited text no. 15


  [Figure 1], [Figure 2], [Figure 3], [Figure 4]

  [Table 1], [Table 2], [Table 3], [Table 4], [Table 5], [Table 6]

This article has been cited by
1 Impact of obesity in colorectal endoscopic submucosal dissection: single-center retrospective cohort study
Jun Tachikawa,Hideyuki Chiba,Naoya Okada,Jun Arimoto,Keiichi Ashikari,Hiroki Kuwabara,Michiko Nakaoka,Takuma Higurashi,Toru Goto,Atsushi Nakajima
BMC Gastroenterology. 2021; 21(1)
[Pubmed] | [DOI]
2 Sedasyon Uygulanan Gastroskopik Girisimlerde Aneminin Integrated Pulmonary Index (IPI ) Skoruna Etkisi
Akademik Gastroenteroloji Dergisi. 2020;
[Pubmed] | [DOI]
3 Use of Noninvasive Positive Pressure Ventilation in Patients with Severe Obesity Undergoing Esophagogastroduodenoscopy: A Randomized Controlled Trial
Makram Gedeon,Sheldon Gomes,Karen Roy,Patricia Duclos-Miller,Jennifer S. Rose
Surgery for Obesity and Related Diseases. 2019;
[Pubmed] | [DOI]
4 High-flow nasal cannula oxygen therapy and hypoxia during gastroscopy with propofol sedation: a randomized multicenter clinical trial
Yuxuan Lin,Xiaoqing Zhang,Lizhi Li,Mengyun Wei,Bin Zhao,Xiaojing Wang,Zhiying Pan,Jie Tian,Weifeng Yu,Diansan Su
Gastrointestinal Endoscopy. 2019; 90(4): 591
[Pubmed] | [DOI]
5 Anesthesia Related Complications of Gastrointestinal Endoscopies; A Retrospective Descriptive Study
Ahmad Hormati,Abolfazl Mohammadbeigi,Seyed Mojtaba Mousavi,Mohammad Saeidi,Hamed Shafiee,Reza Aminnejad
Middle East Journal of Digestive Diseases. 2019; 11(3): 147
[Pubmed] | [DOI]
6 High-flow versus standard nasal cannula in morbidly obese patients during colonoscopy: A prospective, randomized clinical trial
Christina A. Riccio,Stephen Sarmiento,Abu Minhajuddin,Dawood Nasir,Amanda A. Fox
Journal of Clinical Anesthesia. 2019; 54: 19
[Pubmed] | [DOI]
7 Critical analysis of guidelines for providing sedation to patients undergoing gastrointestinal endoscopy procedures
Basavana Goudra,PreetMohinder Singh
Anesthesia: Essays and Researches. 2019; 13(4): 601
[Pubmed] | [DOI]
8 A review of the safety and efficacy of inhaled methoxyflurane as an analgesic for outpatient procedures
C. Jephcott,J. Grummet,N. Nguyen,O. Spruyt
British Journal of Anaesthesia. 2018;
[Pubmed] | [DOI]
9 Reply to “State of the Art in Airway Management During GI Endoscopy: The Missing Pieces”
Basavana Goudra,Preet Mohinder Singh
Digestive Diseases and Sciences. 2017; 62(5): 1388
[Pubmed] | [DOI]
10 Association between Type of Sedation and the Adverse Events Associated with Gastrointestinal Endoscopy: An Analysis of 5 Years’ Data from a Tertiary Center in the USA
Basavana Goudra,Ahmad Nuzat,Preet Mohinder Singh,Anuradha Borle,Augustus Carlin,Gowri Gouda
Clinical Endoscopy. 2017; 50(2): 161
[Pubmed] | [DOI]
11 Enhanced recovery after bariatric surgery
Adrian Alvarez,Basavana G. Goudra,Preet Mohinder Singh
Current Opinion in Anaesthesiology. 2017; 30(1): 133
[Pubmed] | [DOI]
12 Obstructive Sleep Apnea Increases the Risk of Cardiopulmonary Adverse Events Associated with Ambulatory Colonoscopy Independent of Body Mass Index
Vaishali A. Patel,Paul St. Romain,Juan Sanchez,Deborah A. Fisher,Ryan D. Schulteis
Digestive Diseases and Sciences. 2017; 62(10): 2834
[Pubmed] | [DOI]
13 Society of Anesthesia and Sleep Medicine Guidelines on Preoperative Screening and Assessment of Adult Patients With Obstructive Sleep Apnea
Frances Chung,Stavros G. Memtsoudis,Satya Krishna Ramachandran,Mahesh Nagappa,Mathias Opperer,Crispiana Cozowicz,Sara Patrawala,David Lam,Anjana Kumar,Girish P. Joshi,John Fleetham,Najib Ayas,Nancy Collop,Anthony G. Doufas,Matthias Eikermann,Marina Englesakis,Bhargavi Gali,Peter Gay,Adrian V. Hernandez,Roop Kaw,Eric J. Kezirian,Atul Malhotra,Babak Mokhlesi,Sairam Parthasarathy,Tracey Stierer,Frank Wappler,David R. Hillman,Dennis Auckley
Anesthesia & Analgesia. 2016; 123(2): 452
[Pubmed] | [DOI]
14 Practical considerations in the development of a nonoperating room anesthesia practice
Basavana Goudra,Adrian Alvarez,Preet Mohinder Singh
Current Opinion in Anaesthesiology. 2016; 29(4): 526
[Pubmed] | [DOI]
15 Acute pain management in morbid obesity – an evidence based clinical update
Adele Sandra Budiansky,Michael P. Margarson,Naveen Eipe
Surgery for Obesity and Related Diseases. 2016;
[Pubmed] | [DOI]
16 Minor Anesthesia-Related Events During Radiofrequency Ablation for Barrett’s Esophagus Are Associated with an Increased Number of Treatment Sessions
Meir Mizrahi,Neil Sengupta,Douglas K. Pleskow,Ram Chuttani,Mandeep S. Sawhney,Tyler M. Berzin
Digestive Diseases and Sciences. 2016;
[Pubmed] | [DOI]
17 Guidelines for Perioperative Care in Bariatric Surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations
A. Thorell,A. D. MacCormick,S. Awad,N. Reynolds,D. Roulin,N. Demartines,M. Vignaud,A. Alvarez,P. M. Singh,D. N. Lobo
World Journal of Surgery. 2016;
[Pubmed] | [DOI]
18 Sleep-disordered breathing and the patient undergoing endoscopy: Considerations for optimization of periprocedural care
Joshua H. Atkins
Techniques in Gastrointestinal Endoscopy. 2016;
[Pubmed] | [DOI]
19 Does Obstructive Sleep Apnea Influence Perioperative Outcome? A Qualitative Systematic Review for the Society of Anesthesia and Sleep Medicine Task Force on Preoperative Preparation of Patients with Sleep-Disordered Breathing
Mathias Opperer,Crispiana Cozowicz,Dario Bugada,Babak Mokhlesi,Roop Kaw,Dennis Auckley,Frances Chung,Stavros G. Memtsoudis
Anesthesia & Analgesia. 2016; 122(5): 1321
[Pubmed] | [DOI]
20 Controversies in Perioperative Anesthetic Management of the Morbidly Obese: I Am a Surgeon, Why Should I Care?
Ashish C. Sinha,Preet Mohinder Singh
Obesity Surgery. 2015;
[Pubmed] | [DOI]
21 Noninvasive Ventilation During Procedural Sedation in the Emergency Department: A Case Series
Reuben J. Strayer,Nicholas D. Caputo
The American Journal of Emergency Medicine. 2014;
[Pubmed] | [DOI]


    Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article
   Materials and Me...
   Article Figures
   Article Tables

 Article Access Statistics
    PDF Downloaded858    
    Comments [Add]    
    Cited by others 21    

Recommend this journal