|LETTER TO EDITOR
|Year : 2021 | Volume
| Issue : 1 | Page : 141
FDA approved ready to use phenylephrine
Pradeep Kumar Bhatia1, Ankur Sharma2
1 Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
2 Department of Trauma and Emergency (Anaesthesia), All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
|Date of Submission||13-Nov-2019|
|Date of Acceptance||19-Oct-2020|
|Date of Web Publication||10-Apr-2021|
Dr. Ankur Sharma
Department of Trauma and Emergency (Anaesthesiology), All India Institute of Medical Sciences, Basni, Jodhpur - 342 005, Rajasthan
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Bhatia PK, Sharma A. FDA approved ready to use phenylephrine. J Anaesthesiol Clin Pharmacol 2021;37:141
With reference to our previous published article, we had recommended that phenylephrine should be available with prefilled syringes in lower strengths (50, 100 mcg/mL, etc.). It would have many benefits, such as being user-friendly, cost-effective, being able to draw up desired drug dilution, thus saving time in an emergent situation and reducing drug wastage compared to using a 10 mg/mL ampoule presently available.
Recently, on October 22, 2019, United States Food and Drug Administration (FDA) has approved the first prepared formulation of phenylephrine hydrocloride injection (Biorphen, Eton Pharmaceuticals) for treatment of hypotension resulting primarily from anesthesia-associated vasodilation. It is available in 0.1 mg/ml strength. Similar to our recommendation, which can be given without dilution, reducing the risk of drug error in stressful medical settings. It also lowers the risk of breach of sterility and reduces waste. It can be stored up to 3 years in the operating room, emergency room, intensive care unit and in crash carts in the hospital.
It can be said that we thought ahead of times.
Financial support and sponsorship
Conflicts of interest
There are no conflicts of interest.
| References|| |
Bhatia P, Kumar R, Sharma A, Chabra S, Mohammed S. A recommendation for cost-effective preparation of phenylephrine. J Anaesthesiol Clin Pharmacol 2018;34:424-5.
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